PUBLICATIONS IN
INTERNATIONAL JOURNALS
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1. Factors Influencing Polymorphic Transition of Hyoscine N-Butyl Bromide.
T.Arafat, M.Saleh and A.Badwan.
Drug Development and Industrial Pharmacy. 14(15-17), 2127- 2142 (1988).
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2. Physicochemical Study of Terfenadine Glassy State.
M.Sheikh Salem, M.Hassan, H.Alkaysi, T.Arafat, A.Abumalooh
and A.Badwan.
International Conference of Pharmaceutical Technology. Paris.
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3. Levelling off the Effect of particle Size on Dissolution in Spironolactone Tablets.
A.Badwan, Nabulsi, M. Saleh, and T.Arafat.
International Conference on Pharmaceutical Technology. Paris.
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4. Bromhexine Determination by Diazotization Using Potentiometric Titration.
T.Arafat.
Analytical Letter, Vol. 2, 1990.
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5. Physicochemical Properties of Ethinyloestradiol
E.Sallam, N. Salman, T. Arafat, and R. Zaru.
6th Pharmaceutical Technology Conference, Paris. June 1992
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6. Dissolution Characteristics of Interactive Powder Mixtures.
E.Sallam, H.Ibrahim, M.Takieddinin, T.Baghal, M.Saket, R.Awad
and T.Arafat.
8th Pharmaceutical Technology Conference, Monte Carlo. June 1994
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7. Studies Relating to the Content Uniformity of Suppositories.
E.Sallam, H.Ibrahim, M.Takieddin M.Saket, R.Awad, T.Arafat
and M. Othman.
Drug Development and Industrial Pharmacy, 15(14-16), 2653-2673, 1989.
8. A Bioequivalence Study of two Products of Ranitidine Tablets.
M.Saket, T.Arafat, R.Awad, H.Ibrahim, M. Saleh, E.Sallam,
S.Zmeili and M.Gharaibeh.
Current Therapeutic Research, Vol. 46, 5, 924-931, 1989.
9. A bioequivalence Study of two Products of Dipyridamole Tablets.
T.Arafat, M.Saket, R.Awad, H.Ibrahim, M.Saleh, M.gharaibeh,
E.Sallam and M.Shber.
International Journal of Clinical Pharmacology Therapy and Toxicology. vol.
27, 11, 564-567, 1989.
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10. Analysis of Ranitidine in Plasma using High Pressure Liquid
Chromatography.
T.Arafat, M.Saket, R.Awad, M.Saleh, E.Sallam and M.Gharaiabeh
Alexandria Journal of Pharmaceutical Science. 1990.
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11. High-Performance Liquid Chromatography (HPLC) Determination of
Nifedipine in Human Serum.
T.Arafat, Y.Al-Qussuis, H.Mouti, S.Zmieli, S.Judeh and O.Shaheen.
Dirasat,Vol. 17, Number 3, 1990.
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12. Terfenadine
A.Badwan, H.Alkaysi, L. Owis, M.Salem and T.Arafat.
"Analytical Profile of Drug Substances" .Vol. 19, 627-661, 1990.
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13. Some Formulation Aspects of Terfenadine Solid Dispersion.
A.Badwan, A.Abumallh, L.Owis, M.Salem, H.Alkaysi and T.Arafat
Eur. J. Pharm. Biopharm, 37(3), 166-170, 1991.
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14. Pharmacokinetics and Pharmacodynamics of Two Commercial Oral Nifedipine
Products.
O.Shaheen, S.Zmeili, Y.Al-Qussuois, T.Arafat and H.Mouti.
International. J. of Clinical Pharmacology, Therapy and Toxocology. Vol.29
(9), 337-341, 1991.
15. A Bioequivalence Study of Two Products of Furosemide Tablets.
R.Awad, T.Arafat, M.Saket, M.Saleh, M.Gharaibeh, S.Zmeili,
E.Sallam, M.Shubair and S.Qobrosi
International J. of Clinical Pharmacology, Therapy and Toxocology.Vol.
30 (1), 18-23, 1992.
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16. Tenoxicam Polymorphic Modifications
L.Nabulsi, L.Owais, T.Arafat and A.Badwan.
6th International Conference on Pharmaceutical Technology, Paris, June, 1992.
17. Pharmacokinetics and Pharmacodynamics of Two Oral Formulations of
Metformin Hydrochloride.
T.Arafat, A.Kaddoumi, M.Shami and M.Yassin.
Advances In Therapy, Vol. 11, No.1, 21-33, 1994.
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18. A Bioequivalence Study of Two Brands Of Captopril Tablets.
T.Arafat, A.Kaddoumi, N.Al-Muhtasib, M.Shami, M.Yassin and
A.Jehanli. Advances In Therapy, Vol. 11, No .6, 320-330, 1994.
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19. A Liquid Chromatographic Method For The Determination of Norfloxacin in
Plasma.
T.Arafat.
Alex. J. Pharma. Sci., Vol. 9(1), February, 1995.
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20. Determination of Cisapride in Biological Samples.
T.Arafat, M.Shami, A.Kaddoumi, A.Badwan and M.Yassin.
Alex. J. Pharma. Sci., Vol., 9(1), February, 1995.
21. Determination of Terfenadine in Commercial Dosage Forms By
Spectrofluorimetry and High Performance Liquid Chromatography
T.Arafat and A.Kaddoumi.
Alex. J. of Pharma. Sci. Vol., 9 (2), 113 , June.1995.
22.Determination of Captopril in Human Blood by an Enzyme - Linked
Immunosorbent Assay.
A. Jehanli, T. Arafat and M. Al-Shami
J.Pharma. Pharmacology, Vol. 48, (914-917), 1996.
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23. Ibubrofen Sustained - Release Dosage Forms.
M.Gharaiabeh, T.Arafat and E. Sallam.
Clinical Drug Investigation, Vol.11, (3), 174 - 183, 1996
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24. Pharmacokinetic and Pharmacodynamic Profiles of Two Brands of Amlodipine
Determined by Enzyme Linked Immmunosorbent Assay
K.Matalka, T.Arafat, T.El-Thaher, K. Qawasmeh, S. Shebli, M.Hamad and
A. Badwan.
J.Pharm. Pharmacol. Commun. Vol. 6, 539- 544, 2000.
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25. Enzyme Linked Immunosorbent Assay for Determination of Amlodipine in
Plasma
K.Matalka, T.El-Thaher , Mohammad Saleem, T.Arafat, , Ahmed Jehanli
and A. Badwan.
J.of Clinical Laoratory Analysis. Vol. 15, 47- 53, 2001.
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26. Assessment of a controlled release hydrophilic matrix formulation for
metoclopramide HCl.
Enas Hasan, Bassam Amro, Tawfiq Arafat, Adnan Badwan
European Journal of Pharmaceutics and Biopharmaceutics 55 (2003) 339-344.
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27. Pharmacokinetics and pharmacodynamics profiles of enalapril maleate in
healthy volunteers following determination of enelapril and enalaprilat by two
specific enzyme immunoassays
T.Arafat, et al. Journal of Clinical Pharmacy and Therapeutics, June {2005}, 30, 1 - 10
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28. Effect of Steric bulk and stereochemistry on the rates of diketopiperazine
formation from N-aminoacyl-2,2-didimethylthiazolidine-4-carboxamidee
(dipeptideamides) – a model for a new prodrug linker system.
Ghadeer A.R. Suaifan , Mary F. Mahon, Tawfiq Arafat, and Michael D.
Threadgill
Tetrahedron 62, (2006) 11245- 11266.
29. A trend of low serum Vit. B12 in Jordanian adults from two ethnic groups in
Amman
Nancy Hakooz, Rana Abu- Dahab, Tawfiq Arafat and Mohammed Hamad.
Jordan Medical Journal, Vol; 40, no: 2 page 80-87 , 2006.
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30. Validated liquid chromatographic–ultraviolet method for the quantitation of
tadalafil in human plasma using liquid–liquid extraction.
Ashok K. Shakya a,∗, Ahmed N.A. Abu-awwad b, Tawfiq A. Arafat b,
Munther Melhim.
J. of Chromatography and biomedical Application
accepted 29 January 2007
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31. Synthetic approach to peptides containing the L-Gln-L Val-D(s) Dmt Motif
Ghadeer A.R. Suaifan , Tawfiq Arafat, and Michael D. Threadgill
Bio0rganic and Medicinal Chemistry, Volume 15, (2007), 3474 - 3488.
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32.Population Pharmacokinetics of Atorvastatin, Simvastatin & Pravastatin
After Oral Administration in Humans
Naser M.Idkaidek , Naji M. Najib, Tawfiq Arafat and Ahmad Al-Ghazawi
Saudi Pharmaceutical Journal, Vol. 16, No. 1, January 2008
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33. Smoking behavior modulates pharmacokinetics of orally administered
clopidogrel
A.M Yousef Ph.D, Tawfiq Arafat, Ph.D, N.R. Bulatova Md. Ph.D, and R.Al-
Zumyli, B.Sc
Journal of Clinical Pharmacy and Therapeutics, (2008) 33, 439- 449.
34. Simultaneous Determination of Triprolidine and Pseudoephedrine in Human
Plasma by Liquid Chromatography-ion trap mass spectrometry
Ashok K. Shakya*1, Tawfiq A. Arafat2¶, Ahmad N. Abu awwad2,Munther
Melhim2, Jafar Al-Ghani2 and Mahmoud J. Yacoub2
Journal of Chromatography B, 2009
35. Tamsulosin quantification in human plasma by high performance liquid
Chromatography coupled to electrospray tandem mass spectrometry
Ashok K. Shakya1, Nancy M. Hakooz, Tawfiq A. Arafat, Ahmed N.A. Abu-
awwad, Jafar AbdEl-Ghani and Munther Melhim
Acta Chromatographica Journal, volu.22, 2010, 99-116
36. Simple and rapid HPLC method for the determination of alfuzosin in human
plasma
Ashok K. Shakya1, Tawfiq A. Arafat, Ahmad Abuawaad, Hamza Al-Hroub,
Munther Melhim
Jordan Journal of Pharmaceutical Sciences, volume 3, 2010, 25-36
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37. Genetic Analysis of Thiopurine Methyl Transferase Polymorphisim in
Jordanian Population
Nancy Hakooz, Tawfiq Arafat, Debbie Payne, William Ollier, Julie Andrews
and William Newman
Poster Presentation in Portugal
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38. Bioadhesive controlled metronidazole release matrix based on chitosan and
xanthan gum.
Eftaiha Ala'a F; Qinna Nidal; Rashid Iyad S; Al Remawi Mayyas M; Al Shami
Munther R; Arafat Tawfiq A; Badwan Adnan A
Marine drugs 2010;8(5):1716-30.
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39. Enhancement of Oral Bioavailability of Insulin in Humans
Adnan Badwan, mayas Remawi, Amani Elsayed, Tawfiq Arafat, Munther
Melhim, Omar Abu Hijleh, and naser Idkaidek,
Neuroendocrinology letters, Volume 30 No,1 , 2009, 101 - 105
40. Effect of Licorice Drink on the Systemic Exposure of Verapamil in Rabbits
Ibraheem D.Al-Deeb, Tawfiq Arafat and Yacoub M. Irshid
Drug Metabolism Letters,2010, 4, 173-179
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41. Effect of Microgravity on the Pharmacokinetics of Ibuprofen in Humans
Nasir Idkaidek,Ph.D.* , Tawfiq Arafat, Ph.D.
Accepted for Publication,in Journal of Clinical Pharmacology, 2011
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42. Influence of Genetic Variation in Enzyme CYP2C19 and the Effect on the
Pharmacokinetic Profile of Lansoprazole, Screening the Allele frequencies of
CYP2C19*1, CYP2C19*2 and CYP2C19*3 in the Jordanian Population.
Nancy Hakooz. Imad Zallom and Tawfiq Arafat
Oral Presentation in Kuwait, 2011
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43. Effect of Mint Drink on metabolism of Nicotine as measured by Nicotine to
Cotinine Ratio in Urine of Jordanian Smoking Volunteers
Abdulrahman Ghazi, Abdulazim Salhab, Tawfiq Arafat, and Yacoub irshaid
Nicotine and Tobaco Research, 2011, (1-7).
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44. The Effect of Ethyl Acetate Extracts of Pomelo Mix on Systemic Exposure of
Verapamil in Rabbits.
Suad Aqel, Yacoub Irshaid, Munir Gharaibeh and Tawfiq Arafat
Drug Metabolism letters, 2011, 5, 92- 98
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45. Genetic polymorphism of CYP2C19 in a Jordanian population:
influence of allele frequencies of CYP2C19*1 and CYP2C19*2
on the pharmacokinetic profile of lansoprazole
Imad Zalloum • Nancy Hakooz • Tawfiq Arafat
Mol. Biol Rep, July 2011,
46. Plasma concentrations of 25-hydroxyvitamin D among Jordanians:
Effect of biological and habitual factors on vitamin D status
Eyad M Mallah1*, Mohammad F Hamad2, Mays A ElManaseer3, Nidal
Qinna2, Nasir M Idkaidek3, Tawfiq A Arafat1and Khalid Z Matalka2
BMC Clinical Pathology 2011, 11:8
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47. Metformin IR versus XR Pharmacokinetics in Humans
Nasir Idkaidek, Tawfiq Arafat, Munther Melhim , Jaafar Alawneh and Nancy
Hakooz
Journal of Bioequivalence & Bioavailability , 2011, 3 (10), 233 -235.
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48. UDP-glucoronosyltransferase 1A4(UGTIA4) polymorphisms in a Jordanian
population.
Nancy Hakooz, Sameh Alzubiedi, Al-Motassem Yousef, Tawfiq Arafat,
Rana Dajani, Nidaa Ababneh, Said Ismail
Mol. Bioi Rep. 25, February, 2012.
49. Saliva versus Plasma Pharmacokinetics, Theory and Application of a Salivary
Excretion Classification System"
Idkaidek, Nasir; Arafat, Tawfiq
Molecular Pharmaceutics, 2012, 9, , 2358 - 2363
50. EFFECT OF LICORICE AND GRAPEFRUIT JUICE ON PARACETAMOL
PHARMACOKINETICS IN HUMAN SALIVA
Nidal A. Qinna 1,*, Eyad M. Mallah 2, Tawfiq A. Arafat 2 and Nasir M.
Idkaidek3
International journal of Pharmacy and Pharmaceutical Sciences , vol. 4, issue 4,
158-162, 2012
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51. High Performance Liquid Chromatographic Determination of Montelukast
Sodium in Human Plasma: Application to Bioequivalence Study
Ashok K. Shakya, Tawfiq A. Arafat, Nancy M. Hakooz, Ahmad N.
Abuawwad, Hamzea Al-Hroub , Munther Melhim
Acta Chromatoghraphia, Accepted, 04/12/2012.
52: Pharmacokinetics of 600 mg Loading Dose of Clopidogrel in Patients
Undergoing Percutaneous Coronary Intervention.
Al-Motasem Yousef, Ola Diab, Tawfiq Arafat, Akram El-Saleh, Hamzah Al-
Hroub.
Journal Of Biomedical Chromatography, Accepted on 27 of September, 2012.
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53. Development and Valdation for some Azoles in Pharmaceutical Preparation
Wael Abu Dayyih, Noor Al saadi, Mohammad Hamad, Eyad Mallah, Khalid
Matalka, and Tawfiq Arafat
International Journal of Pharmaceutical Sciences and Research, 2012, Vol.
3(10)
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54. Simultaneous Determination of Amlodipine and Atorvastatin with Its
Metabolites; Ortho and Para Hydroxy Atorvastatin; in Human Plasma by LC-
MS/MS
Mahmoud Yacoub, Ahmad Abu awwad, Mahmoud Alawi, Tawfiq Arafat
PII: S1570-0232(13)00021-4
Journal of Chromatography B Received date: 28-9-2013
Accepted date: 1-1-2013
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55. A Stability – Indicating High Performance Liquid Chromatographic (HPLC)
Assay for the Determination of Cefachlor in Biological Fluids
Wael A abu Dayyih, Eyad mallah, Fiasel T. Al-Akayleh, Mohammed F.
Hamad and Tawfiq Arafat
Latin American Journal Of Pharmacy.
Accepted Date: 28/02/2013
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56. Population pharmacokinetic analysis of clopidogrel in healthy Jordanian
subjects with emphasis optimal sampling strategy.
Yousef AM, Melhem M, Xue B, Arafat T, Reynolds DK, Wart SA
Biopharm Drug Dispos. 2013 Mar 5. doi: 10.1002/bdd.1839.
.
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57.Method Development, Validation and Bioequivalence of Varenicline in
Human Plasma by Liquid Chromatography Tandem Mass spectrometry
Ayoub Al-Haj, Mahmoud Alawi, Tawfiq Arafat, Mohammad Khair
Hourani, Journal Chromatography B, accepted, 2013.
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58. Development and Validation of a stability –Indicating HPLC Method for
Determination of Buoivacaine in Human Plasma.
Wael Abu Dayyaih, Enas Alkhader, Eyad Mallah and Tawfiq Arafat
International Journal of Pharmaceutical Analysis, 2051-2740, vol.38,
Issue 2, 2013
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59. Study the Influence of Low Fat Content Test Meal on
Cyclobenzaprine Bioavailability in Human Body by Using
LC/MS/MS
Ahmad Abu awwad1, Mahmoud Yacoub2, Mahmoud Alawi3* and
Tawfiq Arafat4
International Journal of Research in Pharmaceutical and Biomedical
Sciences, Vol. 4 (4) Oct – Dec 2013
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60. Saliva versus Plasma Bioequivalence of Paracetamol in
Humans: Validation of Classes I and II Drugs of the Salivary Excretion
Classification System :
Idkaidek, Nasir; Arafat, Tawfiq Drug Res (2014)
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61. Saliva versus Plasma Bioequivalence of Metformin in
Humans: Validation of Classes I and II Drugs of the Salivary Excretion
Classification System :
Idkaidek, Nasir; Arafat, Tawfiq
Drug Res. 2014, vol. 64, page 599-602
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62. Pomegranate Juice Effects on Pharmacokinetic Parameters of
Metronidazole by Using HPLC-MS
Haifa T. Abu Tabeekh, Wael A. Aby Dayyih, Eyad M.Mallah, Nidal A.
Qinna, Riad Awad, Tawfiq A. Arafat
World Journal Of Pharmacy and Pharmaceutical Sciences, Vol. 3,
Issue 7, 150 -164, 2014.
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63.Synthesis of 2-{4-(t-amino-1-yl) but-2-yn-1-yl} oxy-1,3- benzothiazole
derivatives as H3-antagonists.
Ragheed Al-Rahmani, Elham Al-Qaissi, Tawfeeq Arafat, mohammad
Ghattas, Zuhair Muhi-eldeen
JOSR Journal of Pharmacyvol. 4 issue 9 (September 2014) 41 – 49.
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64. Pethidine level In Jordanian Women and their Newborns during Labor
after a Single Intravenous Dose.
Wael Abu Dayyih, Dania El Tannir, Eyad Mallah, Mohammad Hamad,
Naser Idkaidek, Riad Awad, Abdul Fattah Salem, and Tawfiq Arafat
International Journal of Clinical Anesthesiology vol. 2, 1032, 2014
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65. Determination of loperamide in human plasma and saliva by liquid
chromatography-tandem mass spectrometry,
T.A Arafat, B.T Arafat, R. Awad, A. Abu awwad, (2014).
Journal of chromatography B. 972: 81- 88.
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66. Simultaneous Determination of Atorvastatin, Glimepiride and Amlodipine in
Solution and Plasma Matrix Using HPLC/UV Method
Wael Abu Dayyih, Alaa Al-fayez, Lina Altamimi, Eyad Mallah, and Tawfiq
Arafat
Journal of Chemical and Pharmaceutical Research Vol.6 (11), 515- 528,
2014..
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67. Simultaneous Determination of Sildenafil and Glimepiride in Rat Plasma by
Using Lc-Ms Method and their Applications in Pharmacokinetic Interactions
Eyad Mallah1*, Nibras Al Ani1, Wael Abu Dayyih1, Nidal Qinna2, Riad
Awad1, Kamal Sweidan3 and Tawfiq Arafat1
J. Clinical Pharmaceutics , 1,(2), 1007, 2014
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68. Pioglitazone HCL Levels and its Pharmacokinetic Application in Presence of
Sucralose in Animals Serum by HPLC Method
Lina Tamimi, Wael Abu Dayyah, Nidal Qinna, Eyad Mallah and Tawfiq
Arafat
Pharmaceutica Analytica Vol.5, (9), 2014, 1-9
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69. Evidence of reduced oral bioavailability of paracetamol in rats following
multiple ingestion of grapefruit juice
Nidal A. Qinna, Obbei A. Ismail, Tawfiq M. Alhussainy, Naser M. Idkaidek.,
Tawfiq A. Arafat
Eur. J. Drug Metabolism and Pharmacokinetics, 2014.
70. Comparative bioavailability of two different quetiapine doses (50 and 200 mg)
in healthy volunteers by using LC/MS.
Eyad Mallah, Basel Arafat, Ahmad Abu Awwad, Wael Abu Dayyih,
Mohammed Mima and Tawfiq Arafat
Journal of Chemical and Pharmaceutical Research, 2014, 6 (12)559 – 569
71. Simultaneous determination of Paracetamol and its Metabolites in Rat Serum
by HPLC Method and its Application Supplement-Drug Pharmacokinetic
Interaction
Bayan Alkhawaja, Tawfiq Arafat, Eyad Mallah, Nidal Qinna, Naser Idkaidek,
Wael Abu Dayyih, Hamza Alhroub and Adnan Badwan.
International Journal of Pharmaceutical Analysis, vol,39, issue, 2, 2740 -
2751, 2014
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72. Saliva Versus Plasma Bioequivalence of Rosuvastatin in Humans: validation of
Class III Drugs of the Salivary Excretion Classification System.
Naser Idkaidek, Tawfiq Arafat
Drugs Research and Development, Accepted 2014,
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73. Determination of Atorvastatin Pharmacokinetic Parameters by LC/MS-MS
with Traditional Liquorice Beverage.
Teeba Al. Shaikhli1, Wael Abu Dayyih1,*, Eyad Mallah1, Mohammed
Hamad2, Nidal Qinna1, Tawfiq Arafat1,3
Scientific & Academic Publishing, 2015
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74. Saxagliptin Levels and its pharmacokinetic Application in Presence of
Sucralose in Animals Serum by HPLC Method
Wael Abu Dayyih, Lina Tamimi, Eyad Mallah, Kenza Mansour, Tawfiq Arafat,
Mona Bustami International Journal of Pharmacy and Pharmaceutical
Sciences, Vol, 5ssue 9,
1-8, 2015
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75. Cyclopropan Formation Versus Sigmatropic Rearrange products in the
Ethylenediazzacetate Addition to Allyl Thiotetrapyran
Zuhair Muhi-Eldeen, Tawfiq Arafat, Elham Alqaissi
European Journal of Pharmaceutical Research, vol. 2, 1058- 1065, 2015
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76. Serum concentrations of magnesium among Jordanians: Effect of
Cardiovascular disease on magnesium levels.
Sally Oumeish, Eyad Mallah, Wael Abu Dayyah, Mohammed Hamad, Walid
Abu Rayyan, Mona Bustami and Tawfiq Arafat
Journal of Chemical and Pharmaceutical Research, 2015, 7 (11) 499 – 503
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77. Sensitive and Rapid HPLC-Uv method with back extraction step for the
determination of sildenafil in human plasma
Hamzah Al-Hroub, Bayan Alkhawaja, Eman Alkhawaja, Tawfiq Arafat
Journal of Chromatography B, 2015, 1009, 1-6.
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78. Relative Bioavailability of Ciprofloxacin Doses (750 and 1000) mg in healthy
Male Volunteers by using HPLC method
Mallah E, Arafat B, Alkhawaja B, Abu Dayyih W, Abu Awad A, Hroub HA,
and Arafat T.
Journal of Bioequivalence Studies Vol. 1, Issue 1, 1 -6 , 2015
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79. Determination of carbamazepine in rat plasma in the presence of licorice juice
by using HPLC and its pharmacokinetic applications
Moh,d Salemaldajeh, Eyad Mallah, Riad Awad, Basma A. Othman and Tawfiq
Arafat.
Journal of Chemical and Pharmaceutical Research, 2015, 7(12) : 116 – 1216
80. Synthesis and characterization of a-amino – n-phenyl succinimide as precursor
for corresponding thionimides
Ibrahim Al Adham, Zuhair muhi-Eldeen, Elham Al-Kaissi, Tawfiq Arafat,
Bahaa Shafiq
European Journal of Pharmaceutical and Medical Research, vol. 2, (7),
74 - 86, 2015
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81. Liquorice beverages effect on the pharmacokinetic parameters of atorvastatin,
simvastatin, and lovastatin by liquid chromatography- mass spectroscopy
Wael Abu Dayyih, Eyad Mallah, Israa Al-Ani, Tawfiq Arafat
Asian Journal of Pharmaceutical and Clinical Research, vol. 9 Issue 2,
2016
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82. Nationality, Gender, Age and Body Mass Index Influences on Vitamin D
Concentration among Elderly Patients and Young Iraqi and Jordanian in
Jordan.
Biochemistry Research International, Volume, 2016
Hanan Al-Hourani, Wael Abu Dayyih, Eyad Mallah, Mohammed Hamad,
Mohammed Mima, Riad Awad, and Tawfiq Arafat
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83. A study of the Possible Effect of Pomegranate juice on the Pharmacokinetics of
Candesartan in Rat Plasma by using a Bio analytical Method Liquid
Chromatography / Mass Spectrometry (HPLC/Ms/Ms)
International Journal of Pharmacy & Technology, vol. 8, Issue 1, 10200 –
10216, 2016
Ahmed Al-Kawaz, Wael Abu Dayyih, Eyad Mallah, Mohammed Hamad,
and Tawfiq Arafat
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84. Simultaneous Estimation of Esomeprazole and Tadalafil in Pharmaceutical
formulations using High Performance Liquid Chromatography.
Journal of applied pharmaceutical Science Vol 6 (04), pp 052 – 059 April,
2016.
Mohammed Hamad, Ahmed Al-Sharqawee, Wael Abu Dayyih, Eyad Mallah,
and Tawfiq Arafat
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85. Determination of Fenofibric Acid in Human Plasma by LC/MS/MS and
LC-UV
Chromatographia Journal, April 2016
Tawfiq Arafat, Basil Arafat, Ahmad Abu Awwad & Oliver J. Schmitz
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86. Oxidants and Antioxidants As Risk Factors In Young Arabian Male Patients
With Acute Myocardial Infraction
Najah Al-Muhtaseb, Elham Al-Kaissi , Zuhair muhi-Eldeen, , Tawfiq Arafat,
Sabah Al-Muhtaseb, Hani Atiyah.
International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 8, 273-
277, 2016
87. Dose-Dependent Synergistic effect of Pomegranate Juice on the
Bioavailability of Sildenafil in Rats by Using HPLC Method
Latin American Journal of Pharmacy, 35, (6), 1277 – 1284 , 2016
Eyad M. MALLAH , Walid S.A. RAYYAN, Wael A.A. DAYYIH, Feras D.
ELHAJJI, Kenza A. MANSOUR , Ibrahim S. AL-MAJALI & Tawfiq A.
ARAFAT
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88. Study the Influence of Licorice and Pomegranate Drinks on Nicotine
Metabolism in Human Urine by Lc-orbitrap MS
Journal of Pharmaceutical and Biomedical Analysis, 2016
For authors: Ahmad Abu awwad, Tawfiq Arafat, Oliver J. Schmitz*
89- Simultaneous determination of nicotine, cotinine and nicotine N-oxide in
human plasma, semen and sperm by LCOrbitrap MS
Analytical & Bioanalytical Chemistry , 2016
Ahmad Abu awwad, Tawfiq Arafat, Oliver J. Schmitz*
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90. Preparation of chito-oligomers by hydrolysis of chitosan in presence of
zeolite as adsorbent"
marine drugs, , 14, 43, 2016
Khalid A. Ibrahim , Bassam El-Eswed , Khaleel Abu-Sbeih , Tawfeeq Arafat ,
Mahmoud M.H. Al Omari , Fouad H. Darras and Adnan A. Badwan
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91. Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-
regulation of HIF-1α and sphingosine kinase 1
Accepted in Oncotarget
Heba Alshaker; Q.Wang1; yoshiaki.kawano; Tawfiq Arafat; torsten.bohler;
Mathias.Winkler; Colin.Cooper
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92. Investigation of possible pharmacokinetic interaction of metformin with sugar
replacement sweeteners in rats
Journal of Applied Pharmaceutical Science Vol.6, (10), pp 2010 -215 , 2016
Riad Awad, Eyad Mallah, Israa Al-Anni, Wael Abu Dayyih, Zianab Zakarya
and Tawfiq Arafat
93. Saliva Versus Plasma Bioequivalence of Azithromycin in Humans: Validation
of Class 1 Drugs of the Salivary Excretion Classification System
Drugs Research and Development, 2017
Naser Idkaidek, Tawfiq Arafat, Hazim Hamadi, Salim Hamadi
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94. Ring opening of cyclobutane in 1,3-dimethyl-5-methylene barbituric acid
dimer by various nucleophiles
DE GRUYTER, Z. Naturforsch, 2017, 72, (5) b: 377 – 382
Kamal Swiedan, Wael Abu Dayyih, Murad AlDamen, Eyad Mallah, Tawfiq
Arafat, Mustafa El-Abadelah, Hanadi Salih and Wolfgang Voelter
95. Pharmacokinetics and Pharmacodynamics Interaction of Warfarin in the
Presence of Beverage Juices (Licorice and Pomegranate) in Rat Plasma by
Using LC/MS
Latin American Journal of Pharmacy, 36, (6), 1181 – 1192 , 2017
Mohammed Mima, Eyad Mallah, Wael Abudayyih, Feras Elhaji, Hanadi Salih,
Zainab Zakarya, Basma Othman, & Tawfiq Arafat.
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96. Combination of RAD001 (everolimus and docetaxel reduces prostate and
breast cancer cell VEGF production and tumor vascularization
Independently of sphingosine – kinase -1
Heba Alshaker; Q.Wang1; torsten.bohler; Robert Mills, Mathias Winkler;
Tawfiq Arafat; yoshiaki.kawano;, and Dimitri Pshejetski.
SCIENTIFIC REPORTS
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97. Study of forced degradation behavior of amisulpride by LC-MS and NMR and
development of a stability-indicating method
Kamal Sweedan ; Mohammad Elayan ; Dima Sabbah ; Gada Idrees ;
Tawfiq Arafat
Current Pharmaceutical Analysis, vol. 13, 2017
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98. A Liquid Chromatography-Tandem Mass Spectrometry Method for Evaluation
of Two Brands of Enalapril 20 mg Tablets in Healthy Human Volunteers.
Journal of Analytical Methods in Chemistry Volume 2017,
Wael Abu Dayyih, Mohammed Hamad, Ahmad Abu Awwad, Eyad Mallah,
Zainab Zakarya, Alice Abu Dayyih, Tawfiq Arafat.
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99. The Influence of Eruca Sativa (Argula) on on Pharmacokinetics of Sildenafil in
Rats
Neuroendocrinology letters, Volume 38, No. 4, (101- 107), 2017.
Eyad Mallah, Soadad Saleh, Walid Abu Rayyan, Wael Abu Dayyih,
Feras Darwish Alhajji, Mohammed Mimi, Riad Awad, and Tawfiq Arafat.
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100. Saliva Versus Plasma Bioequivalence of Valsartan/ Hydrochlorothiazide in
Humans: Validation of Class II and IV Drugs of the Salivary Excretion
Classification System
Drugs Research and Development, 2017
Naser Idkaidek, Haneen Agha, Tawfiq Arafat.
101. Effects of the Genetic Variants of Organic Cation Transporters 1 and 3 on the
Pharmacokinetics of Metformin in Jordanians
Drug Metab Pers Ther. 2017 Sep 01.
Nancy Hakooz 1 , Yazun Bashir Jarrar 1 , Malik Zihlif 1 , Amer Imraish 1 , Saja
Hamed 1 , Tawfiq Arafat 1
102. The Effect of Some Fruit Juices on Glimeperide Pharmacokinetic in Rat
Plasma by Using High Performance Liquid Chromatography – Mass
Spectrometry, 2017
Mohammed Hamad, Wael Abu Dayyih, Rafif Raad, Alice Abu-Dayyah,
Israa Al-Ani, Eyad Mallah, hanadeh Saleh, Zainab Zakarya and Tawfiq
Arafat.
103. Synthesis , Structural Elucidation of Aminoacetylenicoxyquinazoline and
their Antiproliferative Activities.
Detr Pharma Chemica, 2017, 9 923) :38 – 45
Zuhair Muhi-eldeen, Bara Alani, Elham Al-Kaissi, Sana Bardaweel,
Mohammed Ghattas, Tawfiq Arafat
104. Validation and Determination of Piracetam in Rat Plasma by Using High
Performance Liquid Chromatography UV/ Vis, Spectrometry in Presence of
Pomegranate and Liquorice Juices for Pharmacokinetic Study.
International Journal of Biology, Pharmacy and Allied Sciences, 2017,
Mohammed Hamad, Ruba Al-Jariri, Lina Al Tamimi , Alice Abu-Dayyah,
Wael Abu Dayyih, Eyad Mallah, and Tawfiq Arafat.
105. Establishment and Validation of a sensitive Method for Detection of
Pregabalin in Pharmacological formulation by GC/MS
Current Pharmaceutical Analysis, 2017
Wael Abu Dayyih, Mohammed Hamad, Eyad Mallah, Alice Abu-
Dayyah, Kenza Mansour, Zianab Zakarya, Riad Awad, and Tawfiq Arafat.
106. Method Development of Vildagliptin and Metformin HCl in Pharmaceutical
Dosage form by Reverse Phase-High Performance liquid Chromatography
(RP-HPLC)
Internationa Journal of Pharmaceutical Sciences and Research (IJPSR)
2017
Wael Abu Dayyih, Mohammed Hamad, Eyad Mallah, Alice Abu-
Dayyah, Zianab Zakarya, and Tawfiq Arafat.
107. Tablet Fragmentation without a disintegrant: A novel design approach for
accelerating disintegration and drug release from 3D printed cellulosic tablets
Basel Arafat, Magdalena Wojsz, Abdullah Isreb, Robert Forbes, Mohammed
Isreb, Waqar Ahmed, Tawfiq Arafat, Mohamed Alhnan.
European Journal of Pharmaceutical Sciences, 2018.
108. Analytical and comparative Study about the Impact of Lead Homeostasis
on Cardiovascular Disorders in Humans
Eyad Mallah , Walid Abu Rayyan, Wael Abu Dayyih, Ibrahim Almajali,
Haytham al Qaralleh, Osama Yousef, Nisrene Seder, Mona Bustami, Luay
Abu Qatoosah, and Tawfiq Arafat.
Biomedpharmajournal, 2018.
109. Synthesis , Structural Elucidation and evaluation of antimicrobial activity of
5-ethoxy-2-mercaptobenzimidazole derivatives.
International Journal of Medical Research & Health Sciences, 2018, 7 (5):
117-127
Alaa Alkhafaji, Zuhair Muhi-eldeen, Elham Al-Kaissi, Najah Al-Muhtaseb,
Tawfiq Arafat and Mohammed Ghattas.
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110. Method Development and Validation of Vildagliptin and Metformin in
Pharmaceutical Dosage Form by Reverse Phase – High Performance
Liquid Chromatography (RP-HPLC).
International Journal of Pharmaceutical Sciences and Research, 2018; Vol.
9(7): 2965-2972 .
Wael Abu Dayyih * , M. Hamad , E. Mallah , A. Abu Dayyih , R. Awad,
Z. Zakaria and T. Arafat
111. Solid Phase Synthesis and Antibacterial Activity of an artificial Cyclic
Peptide Containing Two Disulfide Bridges.
Dassan Jaradat, Khalil Saleh, Basma Zaarer, Tawfiq Arafat, Karem Alzoubi,
Samer Altaweel, Eyad Mallah, Moawiya Haddad, Bayan Haimour.
International Journal of Peptide Research and Therapeutics, 2018
112. Influence of Energy Drinks on Pharmacokinetics Parameters of Sildinafil in
Rats.
Biomedicaland Pharmacology Journal, 2018
Mohammad Abdulla, , Eyad . Mallah , Wael Abu Dayyih * , Walid Abu
Rayyan, Feras Darweesh El-Hajji, Mona Bustami, Kenza Mansour, Israa
Al-Ani, Nisreen Seder and T. Arafat
113. Determination of Carbamazapine in rat plasma by using {HPLC} in presence
of some traditional beverages (Tamarind, Mango, Sugarcane, Red Bull) and its
pharmacokinetic applications.
International Journal of Biology, Pharmacy and Allied Sciences. 2018
Reem Emad, Eyad . Mallah , Fatima Shain, Feras Darweesh El-Hajji, Wael
Abu Dayyih, Luay Abu Qatoosah, Dasan, Jaradat , and T. Arafat .
​
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114. The Impact of the Complexity of Cystic Fibrosis in Jordanian Patients on the
Spectrum of Cystic Fibrosis Trans membrane Conductance Regulator
Mutations
Jordan Jornal of Biological Sciences, Vol.11, no. 17, 2018
Mona R. Bustami1,Luay F. Abu-Qatouseh1 , Nagham A. Hussein 2, Walid S.
Aburayyan1, Eyad M. Mallah1, Raeda W. Khalil3 and Tawfiq A. Arafat1*
115. The Level of Acrylamide in Food items and the effect of reheating of fried
and backed foods on Acrylamide levels
Advances in Environmental Biology, vol.12 (11) pages 29 – 31, 2018
Isam Jawad, Tawfiq Arafat and Marwan Al Muwalla.
116. SULPHA-TRANSFERASE (SULT-1A) GENETIC POLYMORPHISM AND
RISK OF BREAST CANCER IN JORDAN
International Journal of Biology Pharmacy and Allied Health
Luay Abu-Qatouseh1 Mona R. Bustami1, Walid S.
Aburayyan1, Eyad M. Mallah1, and Tawfiq A. Arafat1*
117. Factors affecting coenzyme coobalamine (vit. B12) levels in healthy and
patient individuals from Petra rejoin (Jordan)
Clinical Biochemistry
Layali Abu Aladass, Eyad Mallah, Mohammed Hamad, Wael Abu Dayyih,
Nasir Idkaidek, Soadad Saleh, Luay Abu-Qatouseh, Mona Bustami, Tawfiq
Arafat
118. Development and validation of Liquid Chromatography Method for
Determination of Glimperide in Presence of Vimto Soft Drinks in Rats:
Application to Pharmacokinetic Study.
Journal of Pharmacy and Bioallied Sciences, Vo. 11, page, 49 – 50, 2019
Mohammed Hamad, Areej Rahhal, Wael Abu Dayyih, Eyad Mallah, Alice
Abu Dayyih, Zainab Zakaria and Tawfiq Arafat.
119. The effect of Pomegranate and Licorice on Pharmacokinetics of Theophylline
in Rat Plasma
J.Pharma. Sci. 44, 1, 9 – 16, 2019
Alhuda ALANBAKI * , Israa ALANI**, Eyad Mallah* , Zainab
ZAKAREIA* , Tawfiq ARAFAT* , Wael ABU DAYYIH**,
120. Facile synthesis of model 2,4-diaryl-1,3,4-thiadiazino{5,6-h}
Fluoroquinolones
DE GRUYTER, 2019
Mohammed, Abadleh, Tawfiq Arafat, Luay Abuqatoseh, Mustafa
AbadlehFiras Awwadi, and Wolfgang Voelter
​
121. Hypoglycemic Effect of Olive Oil on Patients and healthy individuals in
Jordan
International Journal of Biology, Pharmacy and Allied Sciences, August 2019,
8 (8): 1393 – 1402
Amera Abudhair, Zianab Zakareia, Eyad Mallah, Wael Abudayyhe, Tawfiq
Arafat, and Luay Abu-Qatouseh
​
122. An LC-MS/MS method for determination of triple drugs combination of
valsartan, amlodipine and hydrochlorothiazide in human plasma for
bioequivalence study
Current Pharmaceutical Analysis
Rana Said*, Basel Arafat, Tawfiq Arafat, Eyad Mallah.
​
123. Effects of the genetic variants of organic cation transporters 1 and 3 on the
pharmacokinetics of metformin in Jordanians.
Drug Metab Pers Ther. 2017 Sep 26;32(3):157-162. doi: 10.1515/dmpt-2019
Hakooz N, Jarrar YB, Zihlif M, Imraish A, Hamed S, Arafat T.
124. High performance liquid chromatography – mass spectrometric bioanalytical
method for the determination of dapoxetine in human plasma: application for
bioequivalence study.
Journal of Chromatography B
Rana Said*, Basel Arafat, Tawfiq Arafat
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125. Synthesis and characterization of some derivatives of 1,3-Diisopropyl 1-4-
5-dimethylimidazole-2-zylidine
Current Chemistry litters, April , 2020
Eyad Mallah, Kamal Swedan, Louay AbuAbu-Qattoseh, Tawfiq Arafat, and
Ragendra Joshei
126. Evaluation of lipid lowering effect of milk thistle (silybum marianum) in
comparison with rosuvastatin in rats by using ACE-Alera® analyzer
INTERNATIONAL JOURNAL OF BIOLOGY AND BIOMEDICAL
ENGINEERING DOI: 10.46300/91011.2020.14.13
Fatima shahina , Eyad Mallaha*, Reem Emada , Luay Abu-Qatouseha , Wael
Abu Dayyiha , Feras Darwish El-hajjib , Kenza Mansoora , Mona
Bostamia , Kamal Sweidanc , Tawfiq Arafat .
​
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127. Glycemic and Insulin emic Response of multi-Grain Types of Bread
Marketed ion Jordan
Current Research in Nutrition and Food Science, Vol. 8 (2), 2020
Refat Al-Kurd, Hamed Takruri, Marwan Muwalla, and Tawfiq Arafat
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128. Development and Validation of Montelukast with Grape/Licorice Juices
and its Application to Pharmacokinetic Studies by LC/MS.
Indonesian Journal of Pharmacy VOL 31, (3), 161 – 170, 2020.
Mohammed Hamad, Rafif Raad, Eyad Mallah, Zainab Zakaria ,
Tawfiq Arafat Wael Abu Dayyih.
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129. The Nutritional Value, Energy and Nutrient Contents and Claims of Marketed
Multi-grain Breads
Journal of Food and Nutrition Research, 2020, Vol. 8, No. 10, 600-605
Refat Alkurd1,* , Hamed Takruri , Marwan Muwalla, and Tawfiq Arafat
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130. Reproductive safety assessment of Thymus vulgaris L. extract and
quantification of thymol sulfate in pregnant rats and fetuses using a validated
LC/MS method of analysis
Journal of Applied Pharmaceutical Science Vol. 0(00), pp 001-008,
November, 2020
Zaineh Q. Tafesh , Kenza A. Mansoor , Nidal A. Qinna , Feras D. El-Hajji ,
Tawfiq A. Arafat , Luay F. Abu-Qatouseh , Bayan Y. Ghanim , Iman A.
Basheti and Eyad M. Mallah
​
131. The effect of grape seed and green tea extracts on the pharmacokinetics of
imatinib and its main metabolite, Ndesmethyl imatinib, in rats
BMC Pharmacology and Toxicology (2020) 21:77
Ruba S. Darweesh1* , Tamam El-Elimat , Aref Zayed , Tareq N. Khamis,
Wahby M. Babaresh , Tawfiq Arafat and Ahmed H. Al Sharie
​
132. HIGH PERFORMANCE LIQUID CHROMATOGRAPHY – MASS
SPECTROMETRIC BIOANALYTICAL METHOD FOR
DETERMINATION OF THE COLCHICINE IN HUMAN PLASMA FOR
BIOEQUIVALENCE STUDY APPLICATION
Sapporo Medical Journal Volume 54, Issue 11, November 2020
Eyad Mallah* , Razan Bardees , Luay Abu Qatouseh , Kamal Sweidan,
Basel Arafat , Da'san Jaradat , Tawfiq Arafat
​
133. Age of Natural Menopause Among Jordanian Women and Factors Related to
Premature and Early Menopause
Risk Management and Healthcare Policy y 2021:14 199–207
Mona Bustami, Khalid Z Matalka, Yousef Elyyan, Nagham Hussein, Nour
Hussein, Nayef Abu Safieh, Fida Thekrallah, Eyad Mallah, Luay Abu-
Qatouseh and Tawfiq Arafat
​
134. SIMULTANEOUS DETERMINATION OF ANTIBIOTIC RESIDUES
(ENROFLOXACIN, CIPROFLOXACIN, DOXYCYCLINE AND
CHLORAMPHENICOL) IN MILK OF JORDAN MARKET
Acta Poloniae Pharmaceutica – Drug Research, Vol. 78 No. 1 pp. 11-19, 2021
HASAN Y. MUTI1, DIMA F. KHATER, AHMAD M. KHALAF, AHMAD
N. ABU-AWWAD and TAWFIQ A. ARAFAT